Table 3.
Microfluidic fabrication of 3D scaffolds for tissue engineering, using microparticles and microfibers as building blocks.
| Biomaterial | Microfluidic Design | Cross-Linking Strategy | Tissue Engineering Application | Ref. |
|---|---|---|---|---|
| Alginate | Two-channel fluid jacket microencapsulator bubble formation | Ionic | Cartilage | [66,67] |
| Gelatin, Collagen/gelatin |
Flow-focusing | Chemical | Heart | [68] |
| Bacterial cellulose | Flow-focusing | Wound healing | [69] | |
| Alginate | Flow-focusing | Ionic | Wound healing | [13] |
| RGD-conjugated alginate | Co-axial | Ionic | Kidney | [70] |
| Alginate, GelMA | Co-axial | Photo + ionic | Endometrium repair | [71] |
| Alginate | Flow-focusing | Ionic | General | [72] |
| Gelatin | Flow-focusing | Thermal | General | [73] |
| GelMA | Flow-focusing | Photochemical | General | [14,15] |