Fig. 4.

Statistical analysis of protoeform abundances between cortex and hypothalamus. Principal component analysis (PCA) of proteoform abundances yields (A) two distinct clusters of cortex (blue) and hypothalamus (pink) samples, and (B) candidate proteoforms for differentiating brain tissue types. C, identified proteoform numbers in cortex (blue) and hypothalamus (pink). D, volcano plot for proteoform in cortex and hypothalamus. Proteoforms are named as gene name, followed by starting and ending residue numbers in parentheses, and PTM (if any). PTM, posttranslational modification.