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. 2022 Dec 27;135(22):2656–2666. doi: 10.1097/CM9.0000000000002505

Table 1.

COVID-19 vaccines as emergency use issued by the WHO.

Candidate vaccine Vaccine platform description Developer Number of doses Schedule Route of administration Storage temperature Number of approved countries Potential serious side effects
mRNA-1273 (Spikevax) mRNA Moderna 2 Day 0 + 28 Intramuscular 2–8°C for 30 days, −20°C for 6 months 88 Myocarditis and pericarditis
BNT162b2 (Comirnaty) mRNA Pfizer/BioNTech 2 Day 0 + 21 Intramuscular −70°C 148
COVOVAX (Novavax formulation) Protein subunit Serum Institute of India 2 Day 0 + 21 Intramuscular 2–8°C 5
Nuvaxovid Protein subunit Novavax 2 Day 0 + 21 Intramuscular 2–8°C 39
Ad5-nCov (Convidecia) Replication-defective adenovirus type 5 vector CanSino 2 Day 0 + 21 Intramuscular 2–8°C 10 Thrombotic thrombocytopenia syndrome
Ad26.COV2.S Replication-incompetent human adenovirus type 26 vector Janssen (Johnson & Johnson) 1–2 Day 0 or Day 0 + 56 Intramuscular 2–8°C 113 Thrombotic thrombocytopenia syndrome and Guillain-Barré syndrome
AZD1222 (Vaxzevria) Replication-defective chimpanzee adenovirus vector Oxford/AstraZeneca 1–2 Day 0 or Day 0 + 28 Intramuscular 2–8°C 148 Thrombotic thrombocytopenia syndrome and Guillain-Barré syndrome
Covishield Replication-defective chimpanzee adenovirus vector Serum Institute of India 1–2 Day 0 or Day 0 + 28 Intramuscular 2–8°C 49 Thrombotic thrombocytopenia syndrome and Guillain-Barré syndrome
Covaxin Inactivated Bharat Biotech 2 Day 0 + 14 Intramuscular 2–8°C 14
BBIBP-CorV (Covilo) Inactivated Sinopharm (Beijing) 2 Day 0 + 21 Intramuscular 2–8°C 93
CoronaVac Inactivated Sinovac 2 Day 0 + 14 Intramuscular 2–8°C 56

COVID-19: Coronavirus disease 2019; mRNA: Messenger ribonucleic acid; WHO: World Health Organization. https://covid19.trackvaccines.org/agency/who/.