Table 2.
Optimal cutoff values and summary indices of SPISE performance to predict Insulin Resistance and Metabolic Syndrome in children and adolescents with obesity (n=725).
| Children (Tanner 1-2) (n=432) |
Adolescents (Tanner 3-5) (n=293) |
|||
|---|---|---|---|---|
| Metabolic Syndrome | Insulin Resistance |
Metabolic Syndrome | Insulin Resistance |
|
| Optimal cutoff | 5.7 | 6.3 | 5.4 | 5.4 |
| Sensitivity (%) | 82.6 | 73.2 | 90.4 | 76.1 |
| Specificity (%) | 86.1 | 80.0 | 76.1 | 77.6 |
| Correctly Classified (%) | 83.8 | 75.2 | 79.0 | 74.5 |
| Positive Predicted Value | 61.9 | 72.1 | 64.5 | 73.9 |
| Negative Predicted Value | 94.7 | 80.7 | 94.4 | 79.4 |
| False Positive Fraction | 18.5 | 26.2 | 31.3 | 30.7 |
| False Negative Fraction | 27.4 | 34.7 | 17.2 | 32.9 |
| Positive likelihood ratio | 5.4 | 3.3 | 3.3 | 3.1 |
| Negative likelihood ratio | 0.51 | 0.61 | 0.45 | 0.66 |
| Pre-test probability (prevalence) | 21.5 | 41.9 | 31.2 | 45.7 |
| Post-test probability (having a test positive) | 64%-72% | 52%-62% | 65%-74% | 55%-66% |
| Area Under Curve | 0.873 | 0.795 | 0.895 | 0.800 |