Table 5.
Cardiometabolic profile in pubertal obese patients according to optimal cutoff values of SPISE to predict IR (5.4) and MetS (5.4).
| Insulin Resistance & Metabolic Syndrome | ||||
|---|---|---|---|---|
| Pubertal patients (n=293) | SPISE ≤ 5.4 (n=173) |
SPISE > 5.4 (n=259) |
Mean difference | ES for difference |
| Waist circumference (mm Hg) | 102.1 ± 10.6*** | 86.3 ± 7.8 | 15.1 | 1.75 |
| Systolic Blood Pressure (mm Hg) | 119 ± 14*** | 110 ± 12 | 9.0 | 0.70 |
| Diastolic Blood Pressure (mm Hg) | 74± 9*** | 69 ± 8 | 5.0 | 0.59 |
| Fasting Glucose (mg/dl) | 87.6 ± 8.6 | 84.8 ± 7.5 | 1.5 | (…) |
| Fasting Insulin (uUI/dl) | 16.6 (9.2)*** | 12.0 (8.1) | 4.6 | 0.54‡ |
| HOMA-IR | 3.7 (2.3)*** | 2.4(1.9) | 1.3 | 0.63‡ |
| HOMA-S (%) | 27.4 (17.4) *** | 41.6 (31.0) | -14.2 | 0.54‡ |
| HOMA-β (%) | 275 (272) ** | 206 (209) | 69 | 0.29‡ |
| Disposition Index | 0.74 (0.5) | 0.76 (0.6) | 0.02 | (…) |
| Total Cholesterol (mg/dl) | 173.4 ± 35.4** | 161.6 ± 33.0 | 11.8 | 0.35 |
| HDL-cholesterol (mg/dl) | 41.3 ± 8.4*** | 44.7 ± 9.4 | -5.9 | 0.38 |
| LDL-cholesterol (mg/dl) | 103.1 ± 30.1 | 96.4 ± 28.3 | 7.0 | (…) |
| TG-HDL ratio | 4.2 (1.5) *** | 3.4 (1.2) | 0.7 | 0.60‡ |
| Triglycerides (mg/dl) | 131.9 (78.1)*** | 75.0 (52.2) | 56.9 | 0.89‡ |
Values expressed as mean ± SD and median (IQR). Two-tailed Student’s t test for independent samples. Wilcoxson Rank-sum test. *Significant at P<0.05. ** Significant at P<0.01. *** Significant at P<0.001. †Cohen’s d statistic (normal distributions), except as indicated. ‡Cliff’s δ (non-normal distributions). Values of d of 0.20, 0.50 and 0.80 denote small, medium and large differences. Values of δ are considered small around 0.15, medium around 0.33, and large around 0.47.