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. 2023 Feb 8;14:1106771. doi: 10.3389/fimmu.2023.1106771

Figure 6.

Figure 6

NSC12 could reverse the function of FGF2 in promoting neurite growth and Ca2+ influx in DRG cells. (A) Representative images of cell morphology and neurite growth in DRG cells treated by FGF2 (200 ng/mL) with or without preincubation of NSC12 (10 μmol/L). (B) Quantified results of length of neurites in different groups (n = 4, 5, 3). (C) Quantified results of number of neurites in different groups (n = 14, 14, 14). (D) Fluo-4 fluorescence intensity of F11 cells treated by FGF2 with or without incubation of NSC12. (E) Ca2+ peak increase (ΔF/F0) in F11 cells treated by FGF2 with or without incubation of NSC12 (n = 3 in each group). *P < 0.05, **P < 0.01.