Table 2.

Age structure of study population, crude age-specific incidence rate and age-standardized incidence rate (ASR, European Standard Population 2013) per 100,000 person-years and relative incidence (Rl) between 2010–2012 and 2017–2019 of first-ever, recurrent and all ischemic stroke

Age group	2010–2012		2013–2016		2017–2019		Rl (95% Cl)
(years)	n/n at risk per year	rate (95% Cl)	n/n at risk per year	rate (95% Cl)	n/n at risk per year	rate (95% Cl)
First-ever ischemic stroke
18–54	1,107/4,606,835	24 (23–25)	1,106/4,729,522	23 (23–24)	1,062/4,869,818	22 (21–23)	0.91 (0.86–0.95)
55–64	2,002/1,172,398	171 (166–175)	1,766/1,142,970	154 (151–158)	1,665/1,167,951	143 (139–147)	0.83 (0.80–0.87)
65–74	3,859/978,573	394 (387–402)	3,921/1,085,965	361 (355–367)	3,716/1,110,099	335 (329–341)	0.85 (0.83–0.87)
75–84	5,128/552,322	928 (914–943)	4,652/583,867	797 (785–808)	4,633/664,172	698 (686–709)	0.75 (0.73–0.77)
≥85	4,227/252,504	1,674 (1,645–1,703)	3,932/257,462	1,527 (1,503–1,551)	3,386/261,470	1,295 (1,270–1,320)	0.77 (0.75–0.79)
Total (≥ 18)	16,323/7,562,632	216 (214–218)	15,377/7,799,786	197 (196–199)	14,463/8,073,510	179 (177–181)	0.83 (0.82–0.84)
ASR (≥0)		181 (178–184)		163 (160–165)		146 (143–148)	0.81
Recurrent ischemic stroke
18–54	155/4,606,835	3 (3–4)	126/4,729,522	3 (2–3)	124/4,869,818	3 (2–3)	0.76 (0.66–0.87)
55–64	393/1,172,398	34 (32–35)	331/1,142,970	29 (27–31)	305/1,167,951	26 (24–28)	0.78 (0.71–0.85)
65–74	1,161/978,573	119 (115–123)	1,041/1,085,965	96 (93–99)	904/1,110,099	81 (78–84)	0.69 (0.65–0.72)
75–84	1,991/552,322	361 (351–370)	1,682/583,867	288 (281–295)	1,456/664,172	219 (213–226)	0.61 (0.58–0.63)
≥85	1,724/252,504	683 (664–702)	1,400/257,462	544 (530–558)	1,106/261,470	423 (409–437)	0.62 (0.59–0.65)
Total (≥18) ASR (≥0)	5,416/7,562,632	72 (71−73) 59 (58–61)	4,579/7,799,786	59 (58–60) 48 (47–49)	3,895/8,073,510	48 (47−49) 39 (37–40)	0.67 (0.66−0.69) 0.66
All ischemic stroke
18–54	1,266/4,606,835	27 (27–28)	1,247/4,729,522	26 (26–27)	1,189/4,869,818	24 (24–25)	0.89 (0.85–0.93)
55–64	2,415/1,172,398	206 (201–211)	2,113/1,142,970	185 (181–189)	1,976/1,167,951	169 (165–173)	0.82 (0.79–0.85)
65–74	5,055/978,573	517 (508–525)	4,994/1,085,965	460 (453–466)	4,631/1,110,099	417 (410–424)	0.81 (0.79–0.83)
75–84	7,168/552,322	1,298 (1,280–1,315)	6,370/583,867	1,091 (1,078–1,104)	6,107/664,172	920 (906–933)	0.71 (0.69–0.72)
≥85	6,013/252,504	2,381 (2,347–2,416)	5,364/257,462	2,084 (2,056–2,111)	4,502/261,470	1,722 (1,693–1,751)	0.72 (0.71–0.74)
Total (≥18) ASR (≥0)	21,917/7,562,632	290 (288−292) 242 (239–246)	20,087/7,799,786	258 (256−259) 212 (209–215)	18,405/8,073,510	228 (226−230) 184 (181–187)	0.79 (0.78−0.80) 0.76