Table 5.
Effect of chemotherapy and radiation therapy on the development of primary malignant brain tumors
| Site and treatment | Observed | Expected | O/E | 95% CI |
|---|---|---|---|---|
| All sites | ||||
| Chemotherapy record | ||||
| Yes | 901 | 904.73 | 1 | 0.93–1.06 |
| None/unknown | 4,311 | 4,111.19 | 1.05# | 1.02–1.08 |
| Radiation record | ||||
| Yes | 1,419 | 1,460.83 | 0.97 | 0.92–1.02 |
| None/unknown | 3,793 | 3,555.08 | 1.07# | 1.03–1.1 |
| Prostate | 1,469 | 1,418.71 | 1.04 | 0.98–1.09 |
| Chemotherapy record | ||||
| Yes | 11 | 6.48 | 1.7 | 0.85–3.04 |
| None/unknown | 1,458 | 1,412.23 | 1.03 | 0.98–1.09 |
| Radiation record | ||||
| Yes | 565 | 556.12 | 1.02 | 0.93–1.1 |
| None/unknown | 904 | 862.59 | 1.05 | 0.98–1.12 |
| Breast | 776 | 878.65 | 0.88# | 0.82–0.95 |
| Chemotherapy record | ||||
| Yes | 232 | 245.95 | 0.94 | 0.83–1.07 |
| None/unknown | 544 | 632.7 | 0.86# | 0.79–0.94 |
| Radiation record | ||||
| Yes | 379 | 446.47 | 0.85# | 0.77–0.94 |
| None/unknown | 397 | 432.18 | 0.92 | 0.83–1.01 |
| Melanoma of the skin | 587 | 442.05 | 1.33# | 1.22–1.44 |
| Chemotherapy record | ||||
| Yes | 3 | 2.19 | 1.37 | 0.28–4 |
| None/unknown | 584 | 439.86 | 1.33# | 1.22–1.44 |
| Radiation record | ||||
| Yes | 7 | 2.57 | 2.73# | 1.1–5.62 |
| None/unknown | 580 | 439.48 | 1.32# | 1.21–1.43 |
| Acute lymphocytic leukemia | 24 | 5.14 | 4.67# | 2.99–6.95 |
| Chemotherapy record | ||||
| Yes | 21 | 4.87 | 4.31# | 2.67–6.59 |
| None/unknown | 3 | 0.27 | 11.3# | 2.33–33.02 |
| Radiation record | ||||
| Yes | 5 | 0.78 | 6.42# | 2.08–14.99 |
| None/unknown | 19 | 4.36 | 4.36# | 2.62–6.81 |
CI, confidence interval.
#
Means p < 0.05.