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Domain architecture of DprA protein of selected bacteria. Central Rossmann fold (RF) is conserved and present in all DprA proteins, while the N-terminal SAM domain is common in all DprA except those of Helicobacter pylori and Pyrococcus furiosus. An additional C-terminal DML1 domain is present in the DprA of Deinococcus radiodurans, Mycobacterium tuberculosis, Rhodopseudomonas palustris, Neisseria meningitides, Vibrio cholera, Haemophilus influnzae, and Synechocytosis spp.
