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. 2023 Feb 8;10:1106272. doi: 10.3389/fmed.2023.1106272

TABLE 4.

Comparison of univariate and multivariate analysis of adenoma factors relative to the occurrence of HGD.

Univariate Multivariate
Size
P <0.001 <0.001
OR (95% CI)
≤1 cm 1
1–2 cm 16.408 (10.614–25.363) 13.890 (8.756–22.034)
2–3 cm 63.099 (38.347–103.829) 48.684 (28.641–82.755)
>3 cm 193.326 (113.632–328.913) 165.599 (95.244–287.923)
Morphology
P <0.001 >0.800
OR (95% CI)
Sessile 2.630 (1.678–4.123) 0.957 (0.580–1.579)
Pedunculated 3.818 (2.435–5.984) 0.946 (0.568–1.575)
Flat 1
Amount
P <0.001 <0.05
OR (95% CI)
1 1
2–3 2.131 (1.559–2.914) 1.261 (0.893–1.781)
>3 3.182 (2.238–4.523) 1.582 (1.070–2.339)
Age
P <0.001 <0.05
OR (95% CI)
<50 1
50–64 2.311 (1.477–3.166) 1.866 (1.152–3.022)
>64 3.164 (2.014–4.973) 2.129 (1.300–3.487)
Location
P <0.001 <0.001
OR (95% CI)
Proximal 1
Distal 2.932 (2.118–4.059) 2.252 (1.589–3.190)

HGD, high-grade dysplasia, CI, confidence interval. Distal = descending colon, rectum, and sigmoid colon; proximal = above the descending colon.