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. 2023 Feb 21;13:3007. doi: 10.1038/s41598-023-29991-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Contrast kinetic parameter and k_io maps of a GL261 tumor estimated using the 3D-UTE-GRASP DCE-MRI data acquired with the proposed two flip-angle method and an isotropic 3D resolution. This is a representative case from the test–retest study (n = 7) in which each mouse was scanned twice consecutively with an interval of 30 min. The whole tumor parameter maps of the Scan-2 are from the Scan-2 images registered to the Scan-1 images as shown in Fig. 1.