Table 4.

Overlap ratios of predicted PPIs between different types of link predictors for datasets with 50% of the PPIs removed (Table S6 and S7 show the complete data)

Overlap ratio of predicted PPIs between types of link predictors
Dataset \overlap between	CN-based	L3-based	CN & L3-based	CRA & L3N’($f_1$)
BioGRID Yeast	69%	79 ± 10 %	30 ± 6 %	35%
STRING Yeast	89%	92 ± 2 %	72 ± 6 %	74%
MINT Yeast	43%	72 ± 8 %	32 ± 2 %	34%
BioGRID Human	64%	69 ± 4 %	38 ± 4 %	37%
STRING Human	54%	58 ± 4 %	44 ± 3 %	44%
MINT Human	37%	71 ± 10 %	4 ± 2 %	5%
HuRI	64%	79 ± 7 %	24 ± 3 %	23%

’CN-based’ and ’CRA & L3N’($f_1$)’ denotes the overlap ratio of the predicted PPIs between CN and CRA, and between CRA and L3N’($f_1$) respectively. For ’L3-based’, since there are multiple L3-based predictors (L3, CH2, Sim, L3N’($f_1$), and L3N’($f_2$)), they calculated the overlap ratio for each pair of predictors. We then took the mean of these ratios as the final value, and also computed the standard deviation. The same applies to ’CN & L3-based’ where a CN predictor is compared to an L3-based predictor. Blue color denotes a relatively higher overlap ratio and red a relatively smaller overlap. Ratios are rounded to nearest integers