Fig. 5.
Subcutaneous injection of G5H2 composite hydrogel loaded with human urine-derived stem cell exosomes in rat cranium to establish an in vivo time-release exosomes model. (A) Fluorescence imaging of fluorescently labelled human urine-derived stem cell exosomes in rat cranium over time. (B) Procedures for sustained release of exosomes in vivo. (C) Fluorescence intensity of retained fluorescently labelled exosomes in vivo with time. Data are shown as mean ± standard error (n = 3). (∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.)