Table 2.
Antibacterial screening in terms of the MIC (nmol mL–1) for compounds (V–X)
| Compound | MIC, (nmol mL–1)1 | C log P2 | |
|---|---|---|---|
| Escherichia coli | Staphylococcus aureus | ||
| (Ic) | 12.5 | 6.25 | 1.88 |
| (Ib) | 12.5 | >25 | 1.47 |
| (IIc) | 12.5 | 6.25 | 2.83 |
| (IIb) | 6.25 | 25 | 2.24 |
| (IIIb) | >25 | 12.5 | 2.51 |
| (IVb) | 12.5 | 6.25 | 2.07 |
| Amoxicillin | 25 | 12.5 | |
| Ciprofloxacin | 12.5 | 6.25 | |
1(a) MIC (minimum inhibitory concentration) values represent the average of three readings; (b) calculated with the ACD/Labs website: https://www.acdlabs.com/ . 2ClogP (Lipophilicity Parameters compound) calculated on ACD/Labs website.