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. 2023 Feb 22;32(167):220188. doi: 10.1183/16000617.0188-2022

TABLE 1.

Childhood interstitial lung disease diagnostic assessment based on computed tomography scan pattern

Elementary lesions Distribution Suspected diagnoses
GGO Dense, diffuse Inherited surfactant disorders
GGO, peripheral traction cysts Diffuse Inherited surfactant disorders
GGO, peripheral and/or parenchymal traction cysts, traction bronchiectasis, reticulations Inherited surfactant disorders (older age); autoinflammatory disorders
Diffuse (sometimes ill-defined centrilobular) nodules, diffuse GGO ± alveolar consolidation Patchy Diffuse alveolar haemorrhage
GGO, cysts, honeycombing and reticulations Peripheral Connective tissue diseases, systemic and autoimmune diseases
GGO Paramediastinal, paracardial, middle lobe, lingula (usual); others (aberrant) Persistent tachypnoea of infancy/neuroendocrine cell hyperplasia of infancy
GGO and air trapping Centrilobular Hypersensitivity pneumonitis
Reversed halo sign Organising pneumonia
Crazy paving More intense in lower lobes Pulmonary alveolar proteinosis
Micronodules, hilar lymphadenopathies Lymphatic distribution Sarcoidosis
Centrilobular nodules Diffuse Hypersensitivity pneumonitis

GGO: ground-glass opacities.