Table 3.
ROC Curve Analysis of TRIP MRI Parameters in Differentiating RE from IRE Zones
| Parameters | AUC* | Cut-off Value | Accuracy (%)† | Sensitivity (%)† | Specificity (%)† | PPV (%)† | NPV (%)† |
|---|---|---|---|---|---|---|---|
|
| |||||||
| PE | 0.95 (0.88,1.00) | 24.4 | 88.5 (23/26) | 92.3 (12/13) | 84.6 (11/13) | 85.7 (12/14) | 91.7 (11/12) |
| AUT60 | 0.96 (0.90,1.00) | 308.9 | 88.5 (23/26) | 84.6 (11/13) | 92.3 (12/13) | 91.7 (11/12) | 85.7 (12/14) |
| AUT90 | 0.98 (0.92,1.00) | 520.5 | 96.2 (25/26) | 100 (13/13) | 92.3 (12/13) | 92.9 (13/14) | 100 (12/12) |
| AUT120 | 0.99 (0.96,1.00) | 783.8 | 96.2 (25/26) | 100 (13/13) | 92.3 (12/13) | 92.9 (13/14) | 100 (12/12) |
| AUT150 | 0.99 (0.98,1.00) | 1066 | 96.2 (25/26) | 100 (13/13) | 92.3 (12/13) | 92.9 (13/14) | 100 (12/12) |
| AUT180 | 0.99 (0.98,1.00) | 1343 | 96.2 (25/26) | 100 (13/13) | 92.3 (12/13) | 92.9 (13/14) | 100 (12/12) |
| Ktrans | 0.94 (0.85,1.00) | 0.28 | 84.6 (22/26) | 76.9 (10/13) | 92.3 (12/13) | 90.9 (10/11) | 80 (12/15) |
| Ve | 0.91 (0.80,1.00) | 45.2 | 80.8 (21/26 | 69.2 (9/13) | 92.3 (12/13) | 90 (9/10) | 75 (12/16) |
Note:
*
Data in parentheses are 95% confidence interval.
†
Data in parentheses are raw data. PE = peak enhancement, AUC = area under the ROC curve, PPV = positive predictive value, NPV = negative predictive value, AUT = area under the time-intensity curve.