Table 3.
Influence Factors for NAFLD in Patients with SCZ
| Variables | Univariate Logistic Regression | Multivariate Logistic Regression | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Male Sex | 0.825 | 0.524−1.298 | 0.405 | |||
| Married | 1.432 | 0.825−2.485 | 0.202 | |||
| Divorced | 1.368 | 0.813−2.303 | 0.238 | |||
| Hypertension | 2.374 | 1.283−4.393 | 0.006 | 1.273 | 0.555−2.919 | 0.569 |
| Diabetes | 3.910 | 1.812−8.438 | 0.001 | 4.291 | 1.380−13.342 | 0.012 |
| APP | 1.718 | 1.084−2.722 | 0.021 | 2.261 | 1.11−4.400 | 0.016 |
| Age | 1.004 | 0.986−1.022 | 0.694 | |||
| BMI | 1.536 | 1.389−1.698 | <0.001 | 1.456 | 1.299−1.634 | <0.001 |
| Duration of SCZ | 1.005 | 0.984−1.026 | 0.628 | |||
| Years of education | 0.995 | 0.935−1.060 | 0.880 | |||
| BPRS score | 0.995 | 0.973−1.017 | 0.630 | |||
| Affinity | 0.969 | 0.876−1.072 | 0.544 | |||
| Negative symptoms | 0.998 | 0.938−1.063 | 0.961 | |||
| Positive symptoms | 0.965 | 0.888−1.049 | 0.407 | |||
| Activation | 1.029 | 0.910−1.163 | 0.649 | |||
| Resistance | 0.945 | 0.844−1.058 | 0.323 | |||
| Drug doses | 1.000 | 0.999−1.001 | 0.815 | |||
| ALT | 1.072 | 1.045−1.100 | <0.001 | 1.063 | 1.007−1.122 | 0.027 |
| AST | 1.074 | 1.034−1.115 | <0.001 | 0.984 | 0.906−1.069 | 0.709 |
| ALP | 0.998 | 0.988−1.008 | 0.639 | |||
| GGT | 1.027 | 1.012−1.042 | <0.001 | 0.998 | 0.980−1.017 | 0.833 |
| TC | 1.535 | 1.178−2.000 | 0.001 | 1.123 | 0.675−1.866 | 0.655 |
| HDL | 0.364 | 0.158−0.837 | 0.017 | 1.404 | 0.373−5.279 | 0.615 |
| TG | 1.639 | 1.214−2.213 | 0.001 | 0.928 | 0.669−1.288 | 0.657 |
| ApoA1 | 0.606 | 0.236−1.560 | 0.299 | |||
| ApoB | 55.120 | 14.321−212.148 | <0.001 | 13.134 | 1.115−154.728 | 0.041 |
| Creatinine | 1.001 | 0.984−1.018 | 0.939 | |||
| UA | 1.008 | 1.005−1.011 | <0.001 | 1.004 | 0.999−1.009 | 0.114 |
| Blood glucose | 1.477 | 1.099−1.985 | 0.010 | 1.001 | 0.681−1.471 | 0.998 |
| NLR | 0.778 | 0.603−1.005 | 0.054 | |||
| MLR | 0.108 | 0.006−1.895 | 0.128 | |||
| PLR | 0.994 | 0.988−0.999 | 0.019 | 0.931 | 0.692−1.253 | 0.638 |
Note: Statistically significant P−values are shown in bold.
Abbreviations: APP, antipsychotic polypharmacy; BMI, body mass index; BPRS, Brief Psychiatric Rating Scale (BPRS) scores; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase; TC, total cholesterol; HDL, high-density lipoprotein cholesterol; TG, triglycerides; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; UA, uric acid; PLR, platelet-to-lymphocyte ratio; MLR, monocyte-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio; OR, odds ratio; CI, confidence interval; SCZ, schizophrenia.