Skip to main content
. 2022 Dec 14;16(1):e003730. doi: 10.1161/CIRCGEN.122.003730

Figure 1.

Figure 1.

p38 MAPK pathway in LMNA-related dilated cardiomyopathy. ASK1 indicates apoptosis signal-regulating kinase 1; ATF2, activating transcription factor 2; CDC42, cell division control protein 42 homolog; DAXX, death-associated protein 6; FasL, Fas ligand; Fax, failed axon connection; LMNA, lamin A/C gene; LPS, lipopolysaccharide; MAL, myelin and lymphocyte protein; MAPK, mitogen-activated protein kinase; MAPKAPK2/3, mitogen-activated protein kinase-activated protein kinase 2/3; MEF2, myocyte enhancer factor; MKK3/6, mitogen-activated protein kinase kinase 3/6; MLK1, mixed lineage kinase 1; MyD88, myeloid differentiation primary response 88; RAC1, Ras-related C3 botulinum toxin substrate 1; RIP, receptor-interacting protein; TAK1, transforming growth factor β-activated kinase 1; TLR, Toll-like receptor; TRADD, tumor necrosis factor receptor type 1-associated death domain protein; TRAF2, tumor necrosis factor receptor-associated factor 2; TRAM, TRIF-related adaptor molecule; and TRIF, Toll/interleukin-1 receptor domain-containing adapter-inducing interferon-β.11–13.