TABLE 7.
Number (% of 280) of DSA-positive and %dd-cfDNA positive biopsies by MMDx diagnoses
| MMDx diagnoses | Number | Number DSA-positive(% of row) | Number with %dd-cfDNA ≥1(% of row) |
|---|---|---|---|
| No rejection | 164 | 17 (10%) | 29 (18%) |
| Possible TCMR | 6 | 0 (0%) | 1 (17%) |
| TCMR | 20 | 5 (25%) | 12 (60%) |
| Possible AMR | 10 | 3 (30%) | 2 (20%) |
| Pure AMR | 61 | 25 (41%) | 46 (75%) |
| Mixed (AMR + TCMR) | 19 | 10 (53%) | 14 (74%) |
| All AMR including mixed | 80 | 35 (44%) | 60 (75%) |
| All AMR/mixed/TCMR | 100 | 40 (40%) | 72 (72%) |
Bolding indicates rows with pure AMR or Mixed rejection, bolding and italicization indicates rows with all AMR.
AMR, antibody-mediated rejection; dd-cfDNA, donor-derived cell-free DNA; DSA, donor-specific antibody; MMDx, Molecular Microscope Diagnostic System; TCMR, T cell–mediated rejection.