Table 4.
Comparison of the survivor and non-survivor groups.
| Survivor (n = 306) | Non-survivor (n = 16) | ap | |
|---|---|---|---|
| Median (Q1, Q3) | Median (Q1, Q3) | ||
| Age | 110.2 ± 43.4 | 127.4 ± 61.1 | 0.145 |
| PRISM score | 9 (4–15) | 24 (17–33) | <0.001* |
| PELOD | 10 (5–12) | 30 (15–40) | <0.001* |
| Organ system involvement | 4 (3–5) | 6 (4.5–6) | <0.001* |
| VIS | 15 (10–25) | 105 (55–144) | <0.001* |
| Leukocyte (on admittance) | 10.92 (6.86–15.51) | 16.06 (9.49–27.05) | 0.019* |
| Lymphocyte (on admittance) | 2.83 (0.9–4.42) | 0.9 (0.6–1.44) | 0.001* |
| D-dimer (Ug/mL) (on admittance) | 3.24 (1.38–4.53) | 9 (1.54–16) | 0.024* |
| Lactate (on admittance) | 2 (1.4–2.96) | 4.5 (2.5–13) | <0.001* |
| Lactate (peak) | 2.8 (2–4.1) | 12.7 (5.2–20) | <0.001* |
| Ferritin (on admittance) | 503 (278.45–900.5) | 2216 (1084–18,090) | <0.001* |
| Ferritin (peak) | 659 (400–1211) | 10,956 (2834–21,320) | <0.001* |
| Troponin (on admittance) | 0.07 (0.02–0.27) | 0.24 (0.04–0.47) | 0.173 |
| CK-MB (on admittance) | 3.25 (1.12–12.93) | 5.52 (0.96–21.51) | 0.639 |
| NT-proBNP (on admittance) | 3077 (634–12,405) | 2676 (256–14,000) | 0.739 |
| CRP (on admittance) | 14.1 (2.18–20.4) | 23.76 (12.3–105.39) | 0.008* |
| CRP (peak) | 20.25 (15.15–35.1) | 28.4 (16.68–160.6) | 0.196 |
| PCT (on admittance) | 4.85 (1.31–22.36) | 0.74 (0.43–58.3) | 0.247 |
| PCT (peak) | 8.22 (2.41–31.8) | 3.77 (1.7–58.3) | 0.796 |
| IL-6 (on admittance) | 70 (19–355) | 285 (35.85–652.5) | 0.220 |
| Sedimentation (on admittance) | 45 (23–76) | 60 (26.5–65) | 0.964 |
| Fibrinogen (on admittance) | 461 (273–630) | 309.5 (94–391) | 0.028* |
| n (%) | n (%) | p | |
| Cardiac disease | 259 (84.6) | 15 (93.7) | b0.483 |
| Renal disease | 59 (19.3) | 11 (68.7) | b<0.001* |
| Respiratory disease | 151 (49.3) | 12 (75) | c0.045* |
| Hematological disease | 251 (82) | 16 (100) | b0.084 |
| Neurological disease | 79 (25.8) | 9 (56.2) | b0.017* |
| Severe cardiac impairment EF < 30% | 27 (8.2) | 9 (56.2) | b0.005* |
| Mechanical ventilation | 42 (13.7) | 13 (81.2) | b<0.001* |
PRISM pediatric risk of mortality, PELOD pediatric logistic organ dysfunction, VIS vasoactive inotropic score, CK-MB creatine kinase isoenzyme, NT-proBNP N-terminal pro-brain natriuretic peptide, CRP C-reactive protein, PCT procalcitonin, IL-6 interleukin 6, EF ejection fraction.
*p < 0.05.
aMann–Whitney U-test.
bFisher’s exact test.
cPearson chi-square test.