Skip to main content
. 2023 Feb 21;30(1):2180112. doi: 10.1080/10717544.2023.2180112

Figure 6.

Figure 6.

A. Suppressive effect of mPEG-CS-cRGD/Bmi-1RNAi-PTX on mouse laryngeal carcinoma transplantation tumors. a Tumor volume changes in mice. b We use one-way ANOVA exposure, control vs. other three groups, f(4)=19.12, p < 0.05. c Changes in body weight of mice, we use one-way ANOVA exposure, control vs. two groups, f(4)=6.377, p < 0.01. d H&E staining of mice tumor(200x). e The protein level of Bcl-2 by western blot. B mPEG-CS-cRGD/Bmi-1RNAi-PTX effectively inhibited Bmi-1 expression in vivo and reduced the protein expression levels of ITG αv, ITGβ3, C-myc, Nanog, Oct-4 and Sox-2. a Immunohistochemical analysis of the mice tumor tissue of C-myc. b We use one-way ANOVA exposure, control vs. other three groups, f(4)=64.38, p < 0.001(200x). c The protein level of Bmi-1, ITG αv, ITG β3 and C-myc by western blot.