Figure 3.

DEX administration inhibited airway remodeling in chronic asthmatic mice. Representative images of lung sections stained with Masson trichrome (a), anti-α-SMA antibody (green) (b), and PAS (c) from each group. Scale bar = 100 μm. (d) Quantitative analyses of the percentage of collagen fiber content in lung sections. (e) Quantitative analyses of positive α-SMA staining area, normalized to the perimeter of the basement membrane. (f) PAS score was calculated by the percentage of epithelium positive for PAS staining. Data were presented as mean ± SEM (n = 5~8 animals). ^∗P < 0.05, ^∗∗P < 0.01, and ^∗∗∗P < 0.001.