Table 2.

Association Between NPAR and All-Cause Mortality in MIMIC Cohort

	Non-Adjusted OR (95% CIs)	P value	Model I OR (95% CIs)	P value	Model II OR (95% CIs)	P value
30-day mortality
NPAR	1.05 (1.04, 1.06)	<0.001	1.05 (1.04, 1.07)	<0.001	1.05 (1.03, 1.06)	<0.001
NPAR tertiles
<22.8	1.0 (ref.)		1.0 (ref.)		1.0 (ref.)
22.8–28.4	1.43 (1.15, 1.77)	<0.001	1.40 (1.12, 1.75)	0.003	1.29 (1.00, 1.67)	0.055
≥28.4	2.35 (1.90, 2.90)	<0.001	2.43 (1.96, 3.00)	<0.001	2.08 (1.58, 2.75)	<0.001
90-day mortality
NPAR	1.06 (1.05, 1.07)	<0.001	1.06 (1.05, 1.07)	<0.001	1.06 (1.04, 1.07)	<0.001
NPAR tertiles
<22.8	1.0 (ref.)		1.0 (ref.)		1.0 (ref.)
22.8–28.4	1.49 (1.22, 1.81)	<0.001	1.46 (1.20, 1.79)	<0.001	1.32 (1.05, 1.67)	0.020
≥28.4	2.36 (1.95, 2.87)	<0.001	2.49 (2.04, 3.04)	<0.001	2.07 (1.61, 2.67)	<0.001
One-year mortality
NPAR	1.04 (1.03, 1.05)	<0.001	1.05 (1.04, 1.06)	<0.001	1.05 (1.03, 1.06)	<0.001
NPAR tertiles
<22.8	1.0 (ref.)		1.0 (ref.)		1.0 (ref.)
22.8–28.4	1.28 (1.06, 1.53)	0.009	1.25 (1.04, 1.51)	0.020	1.15 (0.93, 1.44)	0.197
≥28.4	1.81 (1.50, 2.17)	<0.001	1.90 (1.57, 2.29)	<0.001	1.60 (1.26, 2.04)	<0.001

Notes: Models were all derived from logistic regression models. Non-adjusted model adjusted for none. Model I adjusted for age and gender. Model II adjusted for age, gender, heart failure, hypertension, stroke, temperature, respiration rate, systolic blood pressure, diastolic blood pressure, white blood cell, lymphocyte, hemoglobin, creatinine, SOFA score, anticoagulant, rate control drugs and amiodarone.

Abbreviations: MIMIC, Medical Information Mart for Intensive Care; NPAR, neutrophil percentage-to-albumin ratio; OR, odds ratio; CI, confidence interval; Ref, reference; SOFA, sequential organ failure assessment.