Table 1.

Involvement of immune cells and cytokines in mouse models of arthritis

Model	Immune cell	Cytokine
Collagen-induced arthritis	Monocytes/macrophages, dendritic cells, granulocytes, synoviocytes, T cells, B cells	TNF-α, IL-1β, IL-6, IL-17, IL-23, IL-32, MCP-1, MIP1
Antigen-induced arthritis	Monocytes/macrophages, dendritic cells, granulocytes, synoviocytes, T cells, B cells	TNF-α, IL-1β, IL-6, IL-17, IFN-γ
Proteoglycan-induced arthritis	Monocytes/macrophages,	TNF-α, IL-1β, IL-6, IL-12, MCP-1, MIP1α, MIP-2
	granulocytes, synoviocytes,
	T cells, B cells
Collagen antibody-induced arthritis	Monocytes/macrophages, synoviocytes	IL-1β, IL-6, TNF
HuTNF transgenic mice	Monocytes/macrophages, granulocytes	TNF-α, IL-1β,
IL-1 receptor antagonist knockout mice	Monocytes/macrophages, synoviocytes	IL-1, IL-17

TNF, tumor necrosis factor; IL, interleukin; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; IFN, interferon; HuTNF, human tumor necrosis factor.