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. 2023 Feb 22;14(2):149. doi: 10.1038/s41419-023-05667-6

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© The Author(s) 2023, corrected publication 2023

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Fig. 3 — A Transwell assay showed that MALAT1 knockdown hindered the migration and invasion of SCC15 and UM1 cells. Scale bar, 100 μm. B Representative images of gaps in HNSCC cells transfected with si-MALAT1 and negative control at the beginning (0 h) and the endpoint (24 h) of wound healing assay were shown. MALAT1 depletion retarded the wound-healing process in HNSCC cells. Scale bar, 200 μm. C The immunofluorescence staining of E-cadherin in SCC15 and UM1 cells transfected with MALAT1 siRNAs and negative control, respectively. Scale bar, 20 μm. D The proteins of E-cadherin, N-cadherin, Vimentin and Snail were determined by western blot assay in si-MALAT1-transfected HNSCC cells. E Representative images of immunofluorescence of F-actin and Cortactin in SCC15 cells transfected with si-NC or si-MALAT1 were shown. Scale bar, 20 μm. Data in this figure, mean ± SD, **P < 0.01, ***P < 0.001. NC negative control. si-M si-MALAT1.