Table 2.
Additional mutations compared to the AY.29 wild-type reference sequence.a
| Haplotype 1 | Haplotype 2 (index type) | Haplotype 3 | Haplotype 4 | Haplotype 5 | Haplotype 6 | Haplotype 7 | Haplotype 8 | Haplotype 9 | Haplotype 10 | Haplotype 11 |
|---|---|---|---|---|---|---|---|---|---|---|
| Case 11 | Case 1; 2; 4; 9; 10; 16; 17; 19 | Case 13 | Case 5 | Case 12 | Case 18; 20 | Case 7; 8 | Case 15 | Case 6 | Case 14 | Case 3 |
| F274F (N) | F274F (N) | F274F (N) | F274F (N) | F274F (N) | F274F (N) | F274F (N) | F274F (N) | F274F (N) | F274F (N) | F274F (N) |
| (without G142D (S) compared to AY.29 wild type reference) | G618G (ORF1ab) | S3099L (ORF1ab) | I2501T (ORF1ab) | L3935L (ORF1ab) | A65V (ORF8) | H2659H (ORF1ab) | Y489Y (S) | Y489Y (S) | I3944T (ORF1ab) | |
| L140L (ORF1ab) | A4577T (ORF1ab) | |||||||||
| T1006I (S) |
a
AY.29 was first reported in Japan in April 2021, and the sequence of hCoV-19/Japan/TKYK15779/2021|EPI_ISL_2723567|2021–04 was selected as the reference of the AY.29 wild type.