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. 2023 Feb 9;13:1106315. doi: 10.3389/fcimb.2023.1106315

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Copyright © 2023 Jones, Mangin, Reynolds, Villanueva, Cruz, Versteeg, Keegan, Kendricks, Pollet, Gusovsky, Bottazzi and Hotez

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Left Ventricular End diameter (LVED) after treatment. M-mode images from echocardiographic examination were used to measure LVED in naïve, infected untreated and treated mice at 70dpi, 122dpi, 154dpi and 208dpi during both systole (A) and diastole (B). Panels (C) and (D) illustrate only a subset of treatment groups to better visualize treatment differences between key groups. The grey shaded area represents the mean ± SD of the LVEDs and LVEDd measurement from naïve age matched controls.