Table 1.
LVPWs | LVPWd | |||||||
---|---|---|---|---|---|---|---|---|
Days post infection | 72 | 122 | 154 | 208 | 72 | 122 | 154 | 208 |
Naive | 0.806 ± 0.146 | 0.912 ± 0.157 | 0.851 ± 0.196 | 0.932 ± 0.135 | 0.715 ± 0.075 | 0.742 ± 0.069 | 0.738 ± 0.097 | 0.777 ± 0.122 |
Infected untreated | 1.100 ± 0.149 | 1.200 ± 0.154 | 1.059 ± 0.162 | 0.930 ± 0.168 | 0.789 ± 0.084 | 0.8602 ± 0.071 | 0.818 ± 0.096 | 0.782 ± 0.110 |
Low BNZ | 1.245 ± 0.288 | 1.150 ± 0.312 | 1.107 ± 0.146 | 1.032 ± 0.143 | 0.934 ± 0.340 | 0.864 ± 0.185 | 0.806 ± 0.095 | 0.796 ± 0.074 |
Low E6020 | 1.055 ± 0.117 | 1.138 ± 0.132 | 1.096 ± 0.118 | 0.947 ± 0.217 | 0.809 ± 0.083 | 0.849 ± 0.065 | 0.813 ± 0.076 | 0.790 ± 0.189 |
Low Vaccine (sequential) | 1.118 ± 0.141 | 1.080 ± 0.163 | 1.050 ± 0.126 | 0.981 ± 0.164 | 0.770 ± 0.070 | 0.812 ± 0.045 | 0.833 ± 0.088 | 0.787 ± 0.091 |
Low BNZ + Low Vaccine (sequential) | 1.150 ± 0.152 | 1.098 ± 0.221 | 1.004 ± 0.114 | 0.912 ± 0.133** | 0.878 ± 0.0941 | 0.8326 ± 0.050 | 0.844 ± 0.113 | 0.785 ± 0.045* |
Low vaccine (concurrent) | 1.045 ± 0.123 | 1.145 ± 0.163 | 1.089 ± 0.205 | 0.991 ± 0.202 | 0.749 ± 0.056 | 0.853 ± 0.058**** | 0.800 ± 0.089 | 0.788 ± 0.083$ |
Low BNZ + Low Vaccine (concurrent) | 1.244 ± 0.226 | 1.090 ± 0.171 | 1.135 ± 0.180 | 0.988 ± 0.196* | 0.831 ± 0.086 | 0.851 ± 0.080 | 0.869 ± 0.102 | 0.799 ± 0.104 |
High E6020 | 1.083 ± 0.225 | 1.122 ± 0.244 | 1.207 ± 0.201 | 1.074 ± 0.174 | 0.794 ± 0.124 | 0.844 ± 0.075 | 0.854 ± 0.053 | 0.843 ± 0.099 |
High Vaccine (sequential) | 1.067 ± 0.164 | 1.086 ± 0.141 | 1.245 ± 0.144 | 0.972 ± 0.137% | 0.829 ± 0.102 | 0.868 ± 0.073 | 0.879 ± 0.124 | 0.814 ± 0.085 |
Low BNZ + High Vaccine (sequential) | 1.132 ± 0.130 | 1.096 ± 0.173 | 1.216 ± 0.187 | 1.097 ± 0.228 | 0.858 ± 0.065 | 0.853 ± 0.137 | 0.865 ± 0.111 | 0.846 ± 0.102 |
Curative BNZ | 1.164 ± 0.154 | 1.054 ± 0.081 | 0.944 ± 0.145* | 0.873 ± 0.118**$ | 0.7901 ± 0.060 | 0.806 ± 0.074 | 0.763 ± 0.095 | 0.752 ± 0.064$ |
Left ventricular posterior wall thickness. The mean ± SD of left ventricular wall thickness was measured from M-mode echocardiography images during systole (LVPWs) and diastole (LVPWd). When comparing to 72 DPI, *≤0.05, **≤0.01, ****≤0.0001. When comparing to 122 DPI, $≤0.05,When comparing to 154 DPI %≤0.05.