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. 2023 Feb 9;13:1106315. doi: 10.3389/fcimb.2023.1106315

Table 2.

Left ventricular end diameter during systole and diastole.

LVEDs LVEDd
Days post infection 72 122 154 208 72 122 154 208
Naive 3.081 ± 0.023 3.024 ± 0.277 3.000 ± 0.400 3.048 ± 0.0361 3.941 ± 0.195 3.969± 0.194 4.020± 0.307 4.013 ± 0.246
Infected untreated 2.288 ± 0.196 2.411 ± 0.527 2.542 ± 0.305 2.795 ± 0.401 3.575 ± 0.100 3.672 ± 0.395 3.724 ± 0.188 3.886 ± 0.347
Low BNZ 2.146 ± 0.573 2.643 ± 0.424 2.570 ± 0.370 2.582 ± 0.294 3.425 ± 0.639 3.893 ± 0.217 3.859 ± 0.322 3.825 ± 0.291
Low E6020 2.569 ± 0.038 2.290 ± 0.554 2.630 ± 0.326 3.081 ± 0.619 3.829± 0.334 3.570± 0.384 3.976± 0.300 $$ 4.263± 0.599 $$
Low Vaccine (sequential) 2.352 ± 0.543 2.624 ± 0.479 2.443 ± 0.519 2.608 ± 0.226 3.789 ± 0.295 3.783 ± 0.305 3.581 ± 0.311 3.723 ± 0.239
Low BNZ + Low Vaccine (sequential) 2.374 ± 0.401 2.652 ± 0.621 2.753 ± 0.286 * 2.895 ± 0.351 * 3.573 ± 0.266 3.719 ± 0.317 3.915 ± 0.180 ** 3.959 ± 0.271 *
Low vaccine (concurrent) 2.379 ± 0.485 2.481 ± 0.487 2.694 ± 0.425 2.576 ± 0.446 3.676 ± 0.323 3.712 ± 0.381 3.995 ± 0.335 * 3.819 ± 0.310
Low BNZ + Low Vaccine (concurrent) 2.190 ± 0.539 2.497 ± 0.475 2.550 ± 0.163 2.724 ± 0.393 * 3.618 ± 0.297 3.641 ± 0.183 3.761 ± 0.222 3.911 ± 0.215 $
High E6020 2.272 ± 0.395 2.634 ± 0.577 2.366 ± 0.385 2.613 ± 0.541 3.507 ± 0.257 3.784 ± 0.364 3.729 ± 0.248 3.723 ± 0.350
High Vaccine (sequential) 2.596 ± 0.343 2.633 ± 0.509 2.409 ± 0.378 2.783 ± 0.363 3.725 ± 0.267 3.7740± 0.370 3.770 ± 0.344 3.846 ± 0.220
Low BNZ + High Vaccine (sequential) 2.581 ± 0.279 2.563 ± 0.388 2.363 ± 0.341 2.565 ± 0.378 3.768 ± 0.197 3.713 ± 0.259 3.730 ± 0.228 3.797 ± 0.192
Curative BNZ 2.109 ± 0.398 2.621 ± 0.384 ** 2.932 ± 0.400 ** 3.039 ± 0.341 ** 3.476 ± 0.269 3.695 ± 0.266*** 4.007 ± 0.271** 4.093 ± 0.262**$

Left ventricular end diameter during systole and diastole. The mean ± SD of LVED was measured from M-mode echocardiography images at the end of systole (LVEDs ) and diastole (LVEDd). When comparing to 72 DPI, *≤0.05, **≤0.01. ***≤0.001. When comparing to 122 DPI, $≤0.05, $$≤0.01.