Table 3.

Serum β-HB concentration: Respective clinical interpretation.

0.0–0.5 mmol/L	Generally considered below the threshold of significant ketosis, though some studies have demonstrated positive results with lower degrees of ketonemia (in particular among APOε4- individuals)
0.5–2.5 mmol/L	Generally considered an optimal range for the ketogenic diet
2.5–4 mmol/L	Generally considered an optimal range for a diet supplemented with exogenous ketones
>4 mmol/L	Generally considered supratherapeutic, with concern for side effects at higher doses