TABLE 1.
Information of the functional genes used in this study.
| Categories | Functions | Genes | Sources |
|---|---|---|---|
| Stress response proteins | Proteins that can protect against heat-induced oxidative and environmental stress. | Hsf1 (SC), Skn7, Msn2 (SC), Msn4 | Saccharomyces cerevisiae |
| Msn2 (KM), Hsf1 (KM) | Kluyveromyces marxianus | ||
| Heat shock proteins | Proteins that can protect thermally damaged proteins and improve the thermal stability of soluble proteins, SOD and proton pumps in stressed cells. | Hsp104, Hsp12 | Saccharomyces cerevisiae |
| Hsp10 | Thermus thermophilus HB8 | ||
| SHsp | Pyrococcus furiosus | ||
| Sso2427 | Sulfolobus solfatara | ||
| Gros2, Ibpa, Groes | Thermoanaerobacter tengcongensis MB4 | ||
| ATPases | ATPase can transport hydrogen against the concentration gradient through membrane-integrated glycoproteins and stabilize the intracellular pH. | Pma1, Vma2, Vma3 | Saccharomyces cerevisiae |
| Ubiquitin ligases | Ubiquitin ligases play a significant role in protecting cells against acute proteotoxic stress. | Hul5, Hrd1, Rma1, San1 | Saccharomyces cerevisiae |
| Tte2469 | Thermoanaerobacter tengcongensis MB4 | ||
| Antioxidant enzymes | Antioxidant enzymes are the primary protectors against oxidative damage. | Sod1, Cta1, Ctt1, Tsa1, Ahp1, Prx1 | Saccharomyces cerevisiae |
| Bifunctional glutathione synthase gene (GCSGC) | Streptococcus thermophilus | ||
| Nucleic acid protectors | Nucleic acid protectors are helpful for transcriptional regulation and the establishment of new protein homeostasis. | Cspl | Bacillus coagulans 2–6 |