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. 2023 Feb 6;25(3):124. doi: 10.3892/etm.2023.11823

Figure 1.

Figure 1

Cell growth inhibitory rate of cells following treatment with various concentrations of ADM. HepG2, HepG2/pcDNA3.1, HepG2/ADM and HepG2/ABCG2 cells were treated with various concentrations of ADM for 24 h and the cell growth inhibitory rate was detected using the MTT assay. HepG2, HepG2/pcDNA3.1, HepG2/ADM and HepG2/ABCG2 cell survival decreased in a dose-dependent manner following treatment with different concentrations of ADM, ranging from 0.001 to 50 µg/ml. The cell growth inhibitory rate on HepG2/ADM and HepG2/ABCG2 cells was significantly lower than that in HepG2 and HepG2/pcDNA3.1 cells. Values are expressed as the mean +/- standard deviation (n=3). **P<0.01 vs. HepG2 and HepG2/pcDNA3.1 cells. ADM, Adriamycin; ABCG2, adenosine triphosphate-binding cassette transporter G2.