Table 1.
Demographical and Clinical Features of Included Subjects.
| HC(n=31) | P(n=24) | COPD(n=28) | P_COPD(n=29) | p-value | |
|---|---|---|---|---|---|
| Age | 25(23-38) | 53.5(47.25-61.25) | 61(51.75-67.75) | 66(60.5-72.5) | <0.005a |
| Gender,n (%) | <0.001b | ||||
| female | 19(61.3%) | 9(37.5%) | 5(17.9%) | 4(13.8%) | |
| male | 12(38.7%) | 15(62.5%) | 23(82.1%) | 25(86.2%) | |
| Somkers,n (%) | |||||
| Current smoker | 3(9.7%) | 12(50%) | 7(25%) | 7(24.1%) | <0.001c |
| Former smoker | 0 | 0 | 7(25%) | 15(51.7%) | >0.05 |
| Nonsmoker | 28(90.3%) | 12(50%) | 14(50%) | 7(24.1%) | <0.001d |
| PD(mm) | 2(1-2) | 6.33(4.33-6.92) | 2(1.25-2) | 6.33(5-6.67) | <0.001e |
| BOP% | 2.08(2.08-4.17) | 78.13(71.35-83.33) | 2.08(2.08-4.17) | 81.25(68.75-87.5) | <0.001f |
| Stage(%) | 0.612 | ||||
| II | — | 9(37.5%) | — | 8(27.6%) | |
| III | — | 10(41.7%) | — | 16(55.2%) | |
| IV | — | 5(20.8%) | — | 5(17.2%) | |
| GOLD(%) | 0.712 | ||||
| I | — | — | 3(10.7%) | 6(20.7%) | |
| II | — | — | 11(39.3%) | 10(34.5%) | |
| III | — | — | 9(32.1%) | 7(24.1%) | |
| IV | — | — | 5(17.9%) | 6(20.7%) | |
| BMI(kg/m2) | — | — | 27.35(23.43-29.3) | 23.5(22.1-25.75) | 0.007 |
| FVC(L) | — | — | 2.88(2.51-3.56) | 2.82(2.34-3.67) | 0.943 |
| FEV1(L) | — | — | 1.43(0.99-2.18) | 1.34(0.92-2.12) | 0.472 |
| FEV1% | — | — | 58.31(35.71-73.54) | 53.08(33.56-75.52) | 0.576 |
| Peripheral blood | |||||
| WBC(x109/L) | — | — | 6.3 ± 2.1 | 6.5 ± 1.7 | 0.675 |
| RBC(x1012/L) | — | — | 4.7 ± 0.4 | 4.7 ± 0.4 | 0.797 |
| HGB(g/L) | — | — | 143.4 ± 11.2 | 142.8 ± 12.1 | 0.848 |
| Neutrophil percentages(%) | — | — | 57.2 ± 8.1 | 58.6 ± 10.4 | 0.578 |
| Lymphocyte percentages(%) | — | — | 31.1 ± 6.7 | 30.5 ± 9.9 | 0.799 |
| Monocytes percentages(%) | — | — | 7.5(6.45-10) | 7.7(6.65-9) | 0.958 |
| Eosinophil percentages(%) | — | — | 2.3(1.45-3.85) | 2.3(1.25-2.85) | 0.409 |
| Basophil percentages(%) | — | — | 0.5 ± 0.3 | 0.5 ± 0.2 | 0.706 |
| Neutrophil(x109/L) | — | — | 2.99(2.62-5.125) | 3.8(2.675-4.67) | 0.482 |
| Lymphocyte(x109/L) | — | — | 1.9 ± 0.5 | 2.0 ± 0.7 | 0.719 |
| Monocytes(x109/L) | — | — | 0.43(0.375-0.565) | 0.54(0.48-0.615) | 0.147 |
| Eosinophil(x109/L) | — | — | 0.15(0.08-0.22) | 0.12(0.08-0.205) | 0.567 |
| Basophil (x109/L) | — | — | 0.03(0.02-0.04) | 0.03(0.02-0.05) | 0.333 |
aSignificant difference exists among healthy control group and other groups, significant difference exists between periodontitis group and COPD with periodontitis group.
bSignificant differences exists among healthy control group and other three groups.
c,dSignificant difference exists between healthy control group and periodontitis group.
e,fSignificant difference exists between healthy control group and periodontitis group, significant difference exists between COPD group and periodontitis group, significant difference exists between COPD group and COPD with periodontitis group.
BMI, body mass index; GOLD, grading of pulmonary function; WBC, white blood cell; RBC, red blood cell; PD, probing depth; BOP, bleeding on probing.
HC, health controls; P, patients with periodontitis; COPD, patients with chronic obstructive pulmonary disease; P_COPD, patients with comorbid diseases.