Table 2.
Characteristics of the study population for a selection of the included exposures and the Healthy Aging Index
| Exposure/outcome | Type | Label | Total (n = 2815) | Generation 1960s (n = 459) | Generation 1950s(n = 1155) | Generation 1940s (n = 872) | Generation 1930s (n = 329) | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean/% | SD/n | Mean/% | SD/n | Mean/% | SD/n | Mean/% | SD/n | Mean/% | SD/n | |||
| Demographic exposures | ||||||||||||
| Sex | % | women | 53.3 | 1501 | 59.3 | 272 | 52.5 | 606 | 53.0 | 462 | 48.9 | 161 |
| Agea | AUE | in years | 49.4 | 8.4 | 37.9 | 1.7 | 45.6 | 3.0 | 54.7 | 2.8 | 64.5 | 2.7 |
| Agea | TOE | in years | 5.2 | 0.1 | 5.2 | 0.1 | 5.2 | 0.1 | 5.2 | 0.1 | 5.2 | 0.1 |
| Educational level | % | higher vocational education or university | 26.7 | 752 | 22.4 | 103 | 30.9 | 357 | 24.2 | 211 | 24.6 | 81 |
| Lifestyle exposures | ||||||||||||
| Smoking pack years | AUE | in pack years | 8.8 | 11.5 | 5.2 | 7.0 | 8.4 | 10.3 | 9.9 | 12.8 | 12.0 | 15.2 |
| Smoking pack years | TOE | in pack years | 0.8 | 2.2 | 0.9 | 1.7 | 1.0 | 2.2 | 0.6 | 2.1 | 0.6 | 2.5 |
| Dutch Healthy Diet index 2015 | AUE | on a scale from 0 – 130 | 66.1 | 11.8 | 63.0 | 11.2 | 65.7 | 11.7 | 67.2 | 11.8 | 69.3 | 12.0 |
| Dutch Healthy Diet index 2015 | TOE | on a scale from 0 – 130 | 1.2 | 6.5 | 0.8 | 6.7 | 1.0 | 6.4 | 1.3 | 6.4 | 1.6 | 6.4 |
| Environmental exposures | ||||||||||||
| NO2 concentration | AUE | in ug/m3 | 27.7 | 1.8 | 27.5 | 1.7 | 27.8 | 1.7 | 27.7 | 2.0 | 28.0 | 2.1 |
| NO2 concentration | TOE | in ug/m3 | -1.6 | 0.6 | -1.6 | 0.7 | -1.6 | 0.6 | -1.6 | 0.6 | -1.5 | 0.5 |
| Smoking in participant's environment | % of the time | yes, at home and/or at work | 45.2 | 44.4 | 49.0 | 43.8 | 47.7 | 44.8 | 45.5 | 44.6 | 31.7 | 40.6 |
| Smoking in participant's environment | % | from no to yes | 6.0 | 153 | 7.0 | 28 | 7.2 | 74 | 4.7 | 38 | 4.1 | 13 |
| Biological exposures | ||||||||||||
| Body mass index | AUE | in kg/m2 | 25.6 | 3.5 | 24.6 | 3.3 | 25.4 | 3.4 | 26.0 | 3.4 | 26.6 | 3.5 |
| Body mass index | TOE | in kg/m2 | 0.6 | 0.7 | 0.8 | 0.8 | 0.7 | 0.7 | 0.5 | 0.7 | 0.4 | 0.6 |
| Use of cholesterol lowering medication | % of the time | yes | 5.3 | 14.2 | 1.0 | 5.5 | 3.3 | 10.8 | 7.4 | 16.0 | 12.9 | 21.9 |
| Use of cholesterol lowering medication | % | from no to yes | 12.2 | 342 | 2.8 | 13 | 9.4 | 108 | 16.7 | 146 | 22.8 | 75 |
| Outcome | ||||||||||||
| Healthy Aging Index (crude) | at wave 6 | on a scale from 0 – 10 | 7.2 | 1.8 | 8.2 | 1.3 | 7.7 | 1.5 | 6.7 | 1.8 | 5.5 | 1.8 |
| Age-adjusted Healthy Aging Index | at wave 6 | on a scale from -10 – 10 | 0.0 | 1.6 | 0.0 | 1.3 | 0.0 | 1.5 | 0.0 | 1.7 | 0.0 | 1.8 |
AUE Area-Under-the-Exposure, TOE Trend-Of-the-Exposure
aAge is shown here for descriptive purposes only, as age is not included as an exposure in the analyses, and only used to create the age-adjusted Healthy Aging Index outcome