Table 3. Palladium-Catalyzed Carbonylation to Acrylamidesa.
Reaction conditions: aniline (1.0 mmol), 2 (2.0 mmol), Pd(PPh3)4(2 mol %), NaHCO3 (2.0 equiv), THF (4.0 mL), CO (8 atm), 100 °C, 12 h.
Isolated yield.
Reaction conditions: aniline (1.0 mmol), 2 (2.0 mmol), Pd(PPh3)4(2 mol %), NaHCO3 (2.0 equiv), THF (4.0 mL), CO (8 atm), 100 °C, 12 h.
Isolated yield.