TABLE 3.

C-ter acumulation inside the cells faster than Amblyomin-X. Tumor cells were treated with Alexa-Fluor 488-labeled molecules (20 µM) at indicated times. Fluorescence were monitored by a Molecular Devices ImageXpress Micro Confocal plate-scanning microscope (Molecular Devices, Sunnyvale, CA). Vesicles counts were analyzed using MetaXpress software (Molecular Devices, CA) with Transfluor Application Module.

Cell type	Time (h)	C-ter	Amblyomin-X
SK-MEL-28	0.25	30.84 $\pm$ 17.2	15.13 $\pm$ 2.71
	0.5	35.56 $\pm$ 21.09	29.89 $\pm$ 12.27
	1	62.17 $\pm$ 11.20	35.23 $\pm$ 17.32
	2	558.48 $\pm$ 189.00	139.57 $\pm$ 71.44
	4	1210.74 $\pm$ 379.14	988.76 $\pm$ 409.20
Mia PaCa-2	0.25	4.36 $\pm$ 2.03	0.38 $\pm$ 0.25
	0.5	17.50 $\pm$ 24.63	2.77 $\pm$ 1.96
	1	10.59 $\pm$ 7.15	7.42 $\pm$ 0.81
	2	171.11 $\pm$ 248.57	76.69 $\pm$ 20.72
	4	802.63 $\pm$ 353.12	1672.38 $\pm$ 395.60