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. 2023 Feb 9;12:1065935. doi: 10.3389/fonc.2022.1065935
CSCs cancer stem cells
cryo-EM cryogenic electron microscopy
TMD transmembrane domain
NUDT9 Nudix hydrolase 9
ADPR Adenosine diphosphate ribosyl
AMP adenosine monophosphate
PLIK phospholipase C-interacting kinase
PAX6 paired box 6
MITF melanocyte inducing transcription factor
Raf rapidly accelerated fibrosarcoma
ERK extracellular signal-regulated kinase
JNK c-Jun N-terminal kinases
AP-1 Activator protein 1
CREB cAMP response element-binding protein
EGR-1 early growth response protein 1
ELK1 ETS transcription factor
P2X4 purinergic P2X4
eEF2-k eukaryotic elongation factor-2 kinase
PLCγ2 phospholipase C gamma 2
STIM2 stromal interaction molecule 2
IGF2R insulin like growth factor 2 receptor
TGFBR2 transforming growth factor beta receptor 2
NFAT5 nuclear factor of activated T cells 5
BRAF v-raf murine sarcoma viral oncogene homolog B1
AKT protein kinase B
HIF hypoxia-inducible factor
FOXO3a forkhead box protein O3
Nrf2 nuclear factor erythroid 2–related factor 2
FOXM1 forkhead box M1
E2F1/2 E2F transcription factor ½
CDK1 cyclin dependent kinase 1
PLK1 Polo like kinase 1
CKS1 Cyclin-dependent protein kinase regulatory subunit 1
DBTRG Denver brain tumor research group
ULK1 Unc-51 like autophagy activating kinase 1
ATG7 autophagy related 7
ATG5 autophagy related 5
ATF4 activating transcription factor 4
MLL mixed-lineage leukemia 1
CaMKII Calcium/calmodulin-dependent protein kinase II
PANC-1 pancreatic cancer cells
PKC protein kinase C
MAPK mitogen-activated protein kinase
MEK mitogen-activated ERK kinase
LC3-II microtubule-associated protein 1A/1B-light chain 3 tipe II
ULK1 Unc-51 like autophagy activating kinase 1
AMBRA1 autophagy and Beclin 1 regulator 1
ATG10 autophagy related 10
BECN1 beclin 1
BAX BCL2 associated X
MDA-MB-231 M.D. Anderson-Metastatic Breast 231
AGS adenocarcinoma gastric cell line
MKN45 human gastric adenocarcinoma
BNIP3 BCL2 interacting protein 3
LC3A microtubule-associated protein 1 light chain 3
PTEN Phosphatase and tensin homolog
NOD non-obese diabetic
SCID severe combined immunodeficiency
ccRCC clear cell renal cell carcinoma
IGF insulin-like growth factor
EGFR epithelial growth factor receptor
mTOR mechanistic target of rapamycin
GSK glycogen synthase kinase-3
T-REx 293 tetracycline repressor protein
AN3CA metastatic undifferentiated EC
EMT epithelial-mesenchymal transition
PI3K phosphoinositide 3-kinase
CRISPR clustered regularly interspaced short palindromic repeats
CBA 4-chloro-2-[2-(2-chloro-phenoxy)-acetylamino]-benzoic acid
NBA 4-chloro-2-(2-(naphthalene-1-yloxy) acetamido) benzoic acid
LBA 4-chloro-2-(2-(4-chloro-2-methylphenoxy)propanamido) benzoic acid)
TCF/LEF T cell factor/lymphoid enhancer factor
AKT1 AKT serine/threonine kinase 1
SNAI1 snail family transcriptional repressor 1
MIR150 MicroRNA 150
Rac1 Ras-related C3 botulinum toxin substrate 1
SNARE N-ethylmaleimide-sensitive factor-attachment protein receptor
CYBA Cytochrome B-245 alpha chain
MUC2 Mucin 2, oligomeric mucus/gel-forming
GLI1 GLI family zinc finger 1
MMP-9 matrix metallopeptidase 9
NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells
MMP-2 matrix metalloproteinase-2
TGFβ transforming growth factor β;’RACK1, receptor of activated protein C kinase 1
uPA Urokinase-type plasminogen activator
EGCG Epigallocatechin-3-gallate
RAG-2 recombination activating gene 2 protein
IL2RG interleukin 2 receptor subunit gamma
SOX4 SRY-Box transcription factor 4
BAPTA-AM 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester)
HK2 Hexokinase 2
PDK1 phosphoinositide-dependent kinase-1
IDH3B isocitrate dehydrogenase NAD(+) 3 non-catalytic subunit beta
UQCRC1 Ubiquinol-Cytochrome C reductase core protein 1
ECAR extracellular acidification rate
OCR oxygen consumption rate
18F-FDG fluorodeoxyglucose F 18
NFAT nuclear factor of activated T-cells
NFATC nuclear factor of activated T cells 3
Notch 1 Notch homolog 1 translocation-associated
c-myc cellular myelocytomatosis oncogene
SOX2 SRY-Box transcription factor 2
Oct-4 octamer-binding transcription factor 4
STAT3 signal transducer and activator of transcription 3
CAV1 Caveolin 1
ITGA4 Integrin subunit alpha 4
ITGB7 integrin subunit beta 7
2-APB 2-aminoethyl diphenyl borinate
GBM glioblastoma
BCTC 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide
AMTB N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide
Cdc42 cell division cycle 42 protein
FAK focal adhesion kinase
Rap-1A Ras-related protein 1
BK big potassium
Cdk4 Cyclin-dependent kinase 4
TNM tumour, node, metastasis (staging cancer).