CSCs |
cancer stem cells |
cryo-EM |
cryogenic electron microscopy |
TMD |
transmembrane domain |
NUDT9 |
Nudix hydrolase 9 |
ADPR |
Adenosine diphosphate ribosyl |
AMP |
adenosine monophosphate |
PLIK |
phospholipase C-interacting kinase |
PAX6 |
paired box 6 |
MITF |
melanocyte inducing transcription factor |
Raf |
rapidly accelerated fibrosarcoma |
ERK |
extracellular signal-regulated kinase |
JNK |
c-Jun N-terminal kinases |
AP-1 |
Activator protein 1 |
CREB |
cAMP response element-binding protein |
EGR-1 |
early growth response protein 1 |
ELK1 |
ETS transcription factor |
P2X4 |
purinergic P2X4 |
eEF2-k |
eukaryotic elongation factor-2 kinase |
PLCγ2 |
phospholipase C gamma 2 |
STIM2 |
stromal interaction molecule 2 |
IGF2R |
insulin like growth factor 2 receptor |
TGFBR2 |
transforming growth factor beta receptor 2 |
NFAT5 |
nuclear factor of activated T cells 5 |
BRAF |
v-raf murine sarcoma viral oncogene homolog B1 |
AKT |
protein kinase B |
HIF |
hypoxia-inducible factor |
FOXO3a |
forkhead box protein O3 |
Nrf2 |
nuclear factor erythroid 2–related factor 2 |
FOXM1 |
forkhead box M1 |
E2F1/2 |
E2F transcription factor ½ |
CDK1 |
cyclin dependent kinase 1 |
PLK1 |
Polo like kinase 1 |
CKS1 |
Cyclin-dependent protein kinase regulatory subunit 1 |
DBTRG |
Denver brain tumor research group |
ULK1 |
Unc-51 like autophagy activating kinase 1 |
ATG7 |
autophagy related 7 |
ATG5 |
autophagy related 5 |
ATF4 |
activating transcription factor 4 |
MLL |
mixed-lineage leukemia 1 |
CaMKII |
Calcium/calmodulin-dependent protein kinase II |
PANC-1 |
pancreatic cancer cells |
PKC |
protein kinase C |
MAPK |
mitogen-activated protein kinase |
MEK |
mitogen-activated ERK kinase |
LC3-II |
microtubule-associated protein 1A/1B-light chain 3 tipe II |
ULK1 |
Unc-51 like autophagy activating kinase 1 |
AMBRA1 |
autophagy and Beclin 1 regulator 1 |
ATG10 |
autophagy related 10 |
BECN1 |
beclin 1 |
BAX |
BCL2 associated X |
MDA-MB-231 |
M.D. Anderson-Metastatic Breast 231 |
AGS |
adenocarcinoma gastric cell line |
MKN45 |
human gastric adenocarcinoma |
BNIP3 |
BCL2 interacting protein 3 |
LC3A |
microtubule-associated protein 1 light chain 3 |
PTEN |
Phosphatase and tensin homolog |
NOD |
non-obese diabetic |
SCID |
severe combined immunodeficiency |
ccRCC |
clear cell renal cell carcinoma |
IGF |
insulin-like growth factor |
EGFR |
epithelial growth factor receptor |
mTOR |
mechanistic target of rapamycin |
GSK |
glycogen synthase kinase-3 |
T-REx 293 |
tetracycline repressor protein |
AN3CA |
metastatic undifferentiated EC |
EMT |
epithelial-mesenchymal transition |
PI3K |
phosphoinositide 3-kinase |
CRISPR |
clustered regularly interspaced short palindromic repeats |
CBA |
4-chloro-2-[2-(2-chloro-phenoxy)-acetylamino]-benzoic acid |
NBA |
4-chloro-2-(2-(naphthalene-1-yloxy) acetamido) benzoic acid |
LBA |
4-chloro-2-(2-(4-chloro-2-methylphenoxy)propanamido) benzoic acid) |
TCF/LEF |
T cell factor/lymphoid enhancer factor |
AKT1 |
AKT serine/threonine kinase 1 |
SNAI1 |
snail family transcriptional repressor 1 |
MIR150 |
MicroRNA 150 |
Rac1 |
Ras-related C3 botulinum toxin substrate 1 |
SNARE |
N-ethylmaleimide-sensitive factor-attachment protein receptor |
CYBA |
Cytochrome B-245 alpha chain |
MUC2 |
Mucin 2, oligomeric mucus/gel-forming |
GLI1 |
GLI family zinc finger 1 |
MMP-9 |
matrix metallopeptidase 9 |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
MMP-2 |
matrix metalloproteinase-2 |
TGFβ |
transforming growth factor β;’RACK1, receptor of activated protein C kinase 1 |
uPA |
Urokinase-type plasminogen activator |
EGCG |
Epigallocatechin-3-gallate |
RAG-2 |
recombination activating gene 2 protein |
IL2RG |
interleukin 2 receptor subunit gamma |
SOX4 |
SRY-Box transcription factor 4 |
BAPTA-AM |
1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester) |
HK2 |
Hexokinase 2 |
PDK1 |
phosphoinositide-dependent kinase-1 |
IDH3B |
isocitrate dehydrogenase NAD(+) 3 non-catalytic subunit beta |
UQCRC1 |
Ubiquinol-Cytochrome C reductase core protein 1 |
ECAR |
extracellular acidification rate |
OCR |
oxygen consumption rate |
18F-FDG |
fluorodeoxyglucose F 18 |
NFAT |
nuclear factor of activated T-cells |
NFATC |
nuclear factor of activated T cells 3 |
Notch 1 |
Notch homolog 1 translocation-associated |
c-myc |
cellular myelocytomatosis oncogene |
SOX2 |
SRY-Box transcription factor 2 |
Oct-4 |
octamer-binding transcription factor 4 |
STAT3 |
signal transducer and activator of transcription 3 |
CAV1 |
Caveolin 1 |
ITGA4 |
Integrin subunit alpha 4 |
ITGB7 |
integrin subunit beta 7 |
2-APB |
2-aminoethyl diphenyl borinate |
GBM |
glioblastoma |
BCTC |
4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide |
AMTB |
N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide |
Cdc42 |
cell division cycle 42 protein |
FAK |
focal adhesion kinase |
Rap-1A |
Ras-related protein 1 |
BK |
big potassium |
Cdk4 |
Cyclin-dependent kinase 4 |
TNM |
tumour, node, metastasis (staging cancer). |