. 2023 Jan 31;8(1):e01239-22. doi: 10.1128/msystems.01239-22

TABLE 4.

Relative abundances at phylum level and differentially abundant phyla between microbiota derived from chickens fed a control or 1 g/kg feed berberine-supplemented diet for 12 or 21 days posthatch^a

Phylum	Day 12				Day 21
	Mean relative abundance (%)		Log₂ fold change	Adjusted P value	Mean relative abundance (%)		Log₂ fold change	Adjusted P value
	Control	BBR	Log₂ fold change	Adjusted P value	Control	BBR	Log₂ fold change	Adjusted P value
Jejunum
Actinobacteria	0.127	0.283	0.06	0.950	7.431	5.304	−1.20	0.837
Firmicutes	99.332	97.389	−1.73	0.012	88.828	86.774	1.26	0.837
Proteobacteria	0.540	2.328	−0.06	0.950	3.741	7.922	0.55	0.837
Ileum
Actinobacteria	0.279	0.307	0.19	0.723	3.898	3.762	−0.15	0.941
Firmicutes	99.287	96.897	−0.20	0.723	94.847	90.242	0.14	0.941
Proteobacteria	0.434	2.796	2.08	<0.001	1.255	5.995	1.77	0.147
Cecum
Actinobacteria	0.052	0.057	−0.15	0.895	0.046	0.031	−0.10	0.826
Firmicutes	97.019	72.561	0.14	0.895	95.331	93.153	0.10	0.826
Proteobacteria	2.929	27.381	4.02	0.002	4.623	6.816	0.68	0.239
Colon
Actinobacteria	0.036	0.203	0.70	0.391	0.938	0.514	−0.12	0.957
Firmicutes	99.074	82.184	−0.76	0.275	96.009	85.977	0.12	0.905
Proteobacteria	0.890	17.614	3.83	0.001	3.053	13.509	2.28	0.147

The mean relative abundance and the log₂ fold change (BBR/Control) of the LinDA normalized abundance of each phylum are shown. Bold values indicate statistical significance (P value < 0.05). Control, normal diet; BBR, 1 g berberine/kg-supplemented diet.