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[Preprint]. 2023 Feb 18:2023.02.17.528868. [Version 1] doi: 10.1101/2023.02.17.528868

Figure 6. Methylation gradients in other CpG-dense repeat regions.

Figure 6.

(A) Manhattan plot of CpG density in 33 kb sliding windows (step size = 3.3 kb) across the T2T CHM13 v2.0 reference genome. Windows above 7% CpG density are marked as green dots. Alignment and methylation plots of untargeted reads from the C4 control (R10.4.1_e8.2 nanopores) mapped to (B) the tRNA cluster on chromosome 1 and (C) the 5S rRNA cluster on chromosome 1. Mapped reads are anchored by unique flanking sequence and the two ends of the 5S rRNA cluster are shown separately.