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Cinnamein inhibits the mRNA expression of inducible nitric oxide synthase (iNOS) and TNFα in polyIC-stimulated mouse RAW 264.7 macrophages.
Cells preincubated with different concentrations of cinnamein for 6 h were stimulated with 100 μg/ml poly IC under serum-free condition. After 12 h of stimulation, the mRNA expression of iNOS (A) and TNFα (B) was monitored by real-time PCR. Results are mean + SD of three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001.
