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. Author manuscript; available in PMC: 2023 Feb 23.
Published in final edited form as: Nat Struct Mol Biol. 2022 May 9;29(5):451–462. doi: 10.1038/s41594-022-00764-0

Extended Data Fig. 4. TLS inhibition does not enhance DSB formation during NEIL3-dependent ICL repair.

Extended Data Fig. 4

a, REV1 and HMCES immunodepletion. The extracts used in the replication reactions shown in b were blotted for REV1 and HMCES. Asterisks, non-specific bands.

b, pICLAP was replicated with [α−32P]dATP in the indicated extracts (shown in a). Replication intermediates were analyzed as in Fig. 2a.