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. 2022 Oct 10;114(11):1533–1544. doi: 10.1093/jnci/djac160

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Enrichment of EOC statistically significant CNVs (P < .05) in functional biofeatures in ovarian cancer–related cell types. EOC risk CNVs are statistically significantly enriched in insulators across all ovarian cancer–relevant histotype consensus groups. The total number of risk CNVs in each biofeature per histotype grouping can be found in Supplementary Table 11 (available online). Abbreviations for histotypes are as follows: CCOC = clear cell ovarian cancer; EEC = endometriosis (precursor cell type); FT = fallopian tube secretory epithelial cells (precursor cell type); HGSOC = high-grade serous ovarian cancer; IOSE = immortalized ovarian surface epithelium (precursor cell type); LGSOC = low-grade serous ovarian cancer; MOC = mucinous ovarian cancer. CNV = copy number variants; EOC = epithelial ovarian cancer.