Table 1.

Instrumental variables of obstructive sleep apnea.

SNP	A1	A2	EAF	BETA	SE	P	F
*rs9937053	G	A	0.43	0.104	0.012	4.30 × 10−16	82
#rs10507084	C	T	0.18	0.104	0.016	2.80 × 10−11	42
rs4837016	G	A	0.47	−0.073	0.011	1.50 × 10−08	44
rs10928560	C	T	0.18	−0.083	0.014	2.80 × 10−08	36

SNP is the rsID of genetic variants; A1 is the effect allele; A2 is the other allele; EAF is the effect allele frequency; BETA is the effect size of A1 on the exposure; SE is the standard error of beta; P is the p value of beta; F is the F statistics.

^*rs9937053 is an obesity-related SNP and was removed in the main MR analysis. #rs10507084 is the only genome-wide significant SNP after adjusting for BMI and was used in the single IV analysis.