Chart 12.8. – Antihypertensive medications prescribed to children and adolescents in Brazil.

Medication	Age	Initial dose	Maximum dose	Interval
Clonidine	> 12 to	0.2 mg/day	2.4 mg/day	12 h
Atenolol		0.5-1 mg/kg/dose	2 mg/kg/day (max. 100 mg/day)	12-24 h
Propranolol		1-2 mg/kg/dose	4 mg/kg/day (max. 640 mg/day)	8-12 h
Amlodipine	1-5 years	0.1 mg/kg/dose	0.6 mg/kg/day (max. 5 mg/day)	24 h
	> 6 years	2.5 mg/day	10 mg/day	24 h
Isradipine	Toddler	0.05-0.1 mg/kg/dose	0.6 mg/kg/day (max. 10 mg/day)	8-12 h
Felodipine	> 6 years	2.5 mg/day	10 mg/day	24 h
Nifedipine XL		0.25-0.5 mg/kg/dose	3 mg/kg/day (max. 120 mg/day)	12-24 h
Candesartan	1-5 years	0.02 mg/kg/dose (max. 4 mg/day)	0.4 mg/kg/day (max. 16 mg/day)	12-24 h
Olmesartan	> 6 years	< 35 kg: 10 mg/day	< 35 kg: 20 mg/day	24 h
		> 35 kg: 20 mg/day	> 35 kg: 40 mg/day	24 h
Losartan	> 6 years	0.7 mg/kg/day (max. 50 mg/day)	1.4 mg/kg/day (max. 100 mg/day)	24 h
Valsartan	> 6 years	1.3 mg/kg/day	2.7 mg/kg/day (max. 160 mg/day)	24 h
Prazosine	> 12 years	0.05-0.1 mg/kg/dose	0.5 mg/kg/day	8 h
Furosemide		0.5-2 mg/kg/dose	6 mg/kg/day	4-12 h
Spironolactone		1 mg/kg/dose	3.3 mg/kg/day (100 mg/day)	6-12 h
Chlorthalidone	> 40 kg	0.3 (max. 50 mg/day)	2 mg/kg/day	24 h
Hydrochlorothiazide		1 mg/kg/dose	2 mg/kg/day (max. 37.5 mg/day)
Benazepril	> 6 years	0.2 (max. 10 mg/day)	0.6 mg/kg/day (max. 40 mg/day)	24 h
Captopril	Infant	0.05 mg/kg/dose	6 mg/kg/day	6-24 h
	Toddler	0.5 mg/kg/dose	6 mg/kg/day	8 h
Enalapril	> 1 month	0.08 mg/kg/dose	0.6 mg/kg/day (max. 40 mg/day)	12-24 h
Fosinopril	> 6 years	0.2 mg/kg/dose (max. 10 mg/day)	0.6 mg/kg/day (max. 40 mg/day)	24 h
Lisinopril	> 6 years	0.07 mg/kg/dose (max. 5 mg/day)	0.6 mg/kg/day (max. 40 mg/day)	24 h
Ramipril		1.6 mg/m2/day	6 mg/m2/day	24 h
Hydralazine		0.75 mg/kg/dose	7.5 mg/kg/day (max. 200 mg/day)	6 h
Minoxidil	< 12 years	0.2 mg/kg/dose	50 mg/day	6-8 h
	> 12 years	5 mg/day	100 mg/day

h: hours; Max.: maximum.