Chart 5.5. – Factors modifying risks for hypertensive patients.

Family history or parental history of early-onset hypertension
Very high individual RF, including stage 3 HT
Prior eclampsia/pre-eclampsia
Sleep apnea
Pulse pressure > 60 (in older patients)
Uric acid > 7 mg/dL (men) and > 5.7 mg/dL (women) (LR: I, LE: C)
High-sensitivity C-reactive protein > 2mg/L (LR: I, LE: B)
HR > 80 bpm
Metabolic syndrome*
Sedentary lifestyle
Psychosocial and economic factors
Chronic inflammatory disease

HR: heart rate; HT: hypertension; RF: risk factor. * According to the criteria established by the International Diabetes Federation (IDF), metabolic syndrome requires central obesity, defined as abdominal circumference > 80 cm in women or > 94 cm in men of European or African descent or > 90 cm in men of Asian descent, as well as any two of the following four factors: triglycerides > 150 mg/dL, low HDL-C (< 40 mg/dL in men and < 50 mg/dL in women), hypertension; fasting plasma glucose ≥ 100 mg/dL or previously diagnosed type 2 diabetes mellitus. ²⁸⁹