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Assessment of transitivity among all included trials. (A) Number of patients by treatment comparison. (B) Age by treatment comparison. (C) Male ratio by treatment comparison. (D) Number by tumor types. (E) Age by tumor type. (F) Male ratio by tumor type. Abbreviations: Chemo, chemotherapy; CTLA-4, cytotoxic T-lymphocyte antigen 4 inhibitor; PD-1, programmed cell death 1 inhibitor; PD-L1, programmed cell death ligand 1 inhibitor; TTD, targeted therapy.
