Table 2.
Elksniņš-Finogejevs et al.23 | Forogh et al.17 | Uslu Güvendi et al.18 | Huang et al.24 | Jubert et al.19 | |
---|---|---|---|---|---|
Frequency of injections | Single | Single | Single PRP: one PRP injection; three PRP: three PRP injections with 1-week interval | PRP group: (3 times, 4 ml, every 3 weeks); CS group: single | Single |
Use of ultrasound guidance for verification of injection | Yes | No | No | No | No |
Agent injected | |||||
PRP | 8 ml of PRP | 5 ml of PRP was activated by adding 0.5 ml of a calcium gluconate solution (1 g/10 ml); PRP platelet count was 1501×10³ | Venous blood (18 ml) + 2 ml citrate dextrose was separated as plasma | IA-PRP (3 times, 4 ml, every 3 weeks) | 4 ml autologous PRP, a median value of 0.99×106 platelets/ml |
CS | Triamcinolone acetonide (Kenalog) (1 ml of 40 mg/ml) plus lidocaine (5 ml of 2%) in a single syringe | 1 ml of Depo-Medrol (containing 40 mg of methylprednisolone acetate) | 1 ml suspension containing 6.43 mg of betamethasone dipropionate (equivalent to 5.0 mg of betamethasone) and 2.63 mg of betamethasone sodium phosphate (equivalent to 2.0 mg betamethasone). | IA-CS (1 ml) | 2 ml betamethasone: 6 mg betamethasone sodium phosphate and betamethasone acetate 6 mg (Merck) and 2 ml bupivacaine 0.25% (B. Braun) |
Naderi Nabi et al.20 | Freire et al.21 | Khan et al.25 | Nunes-Tamashiro et al.22 | ||
Frequency of injections | Once a month, for 3 consecutive months | Single | Twice, the second injection was given after 2 months | Single | |
Use of ultrasound guidance for verification of injection | Yes | No | No | No | |
Agent injected | |||||
PRP | 5 ml of PRP | 5 ml of PRP | 5 ml of PRP | Platelet value of 2.5–5 times the number of platelets in 45–50 ml of collected blood | |
CS | 40 mg triamcinolone | 2.5 ml of triamcinolone acetate | 1 ml (40 mg) of triamcinolone acetonide and 4 ml of 1% lidocaine hydrochloride mix | 40 mg (2 ml) of triamcinolone hexacetonide |
CS, corticosteroid; IA, intra-articular; PRP, platelet-rich plasma.