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. 2023 Feb 20;7(3):e0057. doi: 10.1097/HC9.0000000000000057

FIGURE 2.

FIGURE 2

Meaningful responses to setanaxib treatment in the 6 PBC-40 domains within each treatment arm. All patients with PBC-40 data available at baseline and week 24 were included in these analyses (n=103); some patients may have stopped setanaxib treatment before the end of the treatment period. Meaningful responses to setanaxib treatment at week 24 were defined by a 0.5-point change from baseline per item in the domain (for example, in the fatigue domain, a change in score of ≥5.5 points would be considered a meaningful response). Abbreviations: BID, twice daily; OD, once daily; PBC-40, primary biliary cholangitis-40 item questionnaire.