Table 2.
Characteristics of NSCLC patients for SNORD88C in plasma.
| Parameters | Samples, n | SNORD88C expression | |
|---|---|---|---|
| Δ Ct Median (interquartile range) | P-value | ||
| Age (years) | |||
| <62 | 105 | 6.050 (5.280–6.455) | 0.7496 |
| ≥62 | 119 | 5.990 (5.200–6.570) | |
| Gender | |||
| Male | 134 | 6.080 (5.165–6.630) | 0.5101 |
| Female | 90 | 5.990 (5.368–6.368) | |
| Smoking | |||
| No | 111 | 6.070 (5.440–6.460) | 0.6028 |
| Yes | 111 | 5.910 (5.090–6.670) | |
| Not available | 2 | ||
| Drinking | |||
| No | 168 | 6.110 (5.400–6.485) | 0.3914 |
| Yes | 56 | 5.865 (4.970–6.685) | |
| Histology | |||
| AC | 158 | 6.005 (5.285–6.443) | 0.4673 |
| SCC | 47 | 5.880 (5.200–6.690) | |
| Others | 19 | ||
| Tumor size | |||
| ≤6 cm3 | 80 | 6.105 (5.560–6.565) | 0.0490 |
| >6 cm3 | 80 | 5.905 (5.083–6.438) | |
| Not available | 64 | ||
| T stage | |||
| Tis | 8 | 6.175 (5.568–6.782) | 0.0142 |
| T1 | 68 | 6.124 (5.928–6.321) | |
| T2 | 70 | 5.877 (5.651–6.102) | |
| T3 | 17 | 5.625 (5.055–6.194) | |
| T4 | 42 | 5.569 (5.305–5.832) | |
| TX | 19 | ||
| LN meta. | |||
| N0 | 97 | 6.230 (5.665–6.615) | 0.0008 |
| N1 | 17 | 6.290 (5.570–6.695) | |
| N2 | 53 | 5.800 (5.060–6.360) | |
| N3 | 40 | 5.420 (4.873–6.285) | |
| NX | 17 | ||
| Distant meta. | |||
| M0 | 131 | 6.160 (5.550–6.600) | 0.0023 |
| M1 | 91 | 5.790 (5.050–6.360) | |
| MX | 2 | ||
| TNM stage | |||
| 0 | 7 | 6.160 (5.630–6.840) | 0.0100 |
| I | 69 | 6.250 (5.750–6.685) | |
| II | 15 | 6.110 (5.610–6.690) | |
| III | 39 | 5.880 (5.090–6.420) | |
| IV | 92 | 5.800 (5.055–6.368) | |
| Not available | 2 | ||
Bold values represent statistical significance p < 0.05.