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. 2023 Feb 10;14:1094838. doi: 10.3389/fgene.2023.1094838

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Copyright © 2023 Chen, zhao, Chen, Jin, Huang, Zhu, Dai, Yuan, Chen, Tang, Chen, Lin, Ai, Wu, Chen and Qin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of inter-genomic differences between molecular isoforms (A) Waterfall plot of the top 20 mutant genes in the 3 metabolic subtypes (A-1: NMF_1, A-2: NMF_2, A-3: NMF_3). (B) Wordclouds were drawn with size of scripts bound up with amounts of samples containing certain mutant genes in the 3 metabolic subtypes (B-1: NMF_1, B-2: NMF_2, B-3: NMF_3). (C) Correlation heat map to show the degree of correlation between mutant genes in the 3 metabolic subtypes, suggesting that the worse the typing prognosis, the less correlated the mutation is (C-1: NMF_1, C-2: NMF_2, C-3: NMF_3). (D) Volcano map used to demonstrate mutation driver genes in the 3 metabolic subtypes (D-1: NMF_1, D-2: NMF_2, D-3: NMF_3).